scClustViz – Single-cell RNAseq cluster assessment and visualization

Single Cluster Visualization to Optimize Air Traffic Management

In this paper we present an application of single cluster visualization (SCV) a technique to visualize single clusters of high-dimensional data. This method maps a single cluster to the plane trying to preserve the relative distances of feature vectors to the corresponding prototype vector. Thus, fuzzy clustering results representing relative distances in the form of a partition matrix as well ...

Assessment of a cluster of gold nanoparticles effect on cell absorbed dose using the Geant4 toolkit

Introduction: Radiotherapy plays a vital role in cancer treatment. To establish a new potency in radiosensitize tumor cells, delivery of High-Z materials is offered. To date, several simulation geometries have been applied to define simulation sets. The clustering of nanoparticles (NPs) within the cells is a prominent parameter usually ignored in simulation studies. <stro...

Single-Cell RNAseq analysis of infiltrating neoplastic cells at the migrating front of human glioblastoma Authors

RNASeq Analysis

3 Statistical issues 3 3.1 Experimental design . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 3.2 Batch effects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 3.3 Summarizing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 3.4 Normalization . . . ...

Differential inhibition of single and cluster type tumor cell migration.

For the control of tumor metastasis it is important to identify chemical compounds with antimigratory potency. Agents acting against single cell and cluster type migration are necessary for successful antimetastatic therapy. In the present study, the migration of HT-1080 fibrosarcoma cells and OSCORT osteosarcoma cells was compared in a Boyden chamber and in an extracellular matrix (ECM)-based ...